BDBM29995 CHEMBL494350::benzimidazole-based antagonist, 1

SMILES C[C@@H]1CN(CCO)CCN1c1cc2[nH]c(SC(C)(C)C)nc2cc1Cl

InChI Key InChIKey=PRUISXHHETXRED-GFCCVEGCSA-N

Data  10 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 29995   

TargetNociceptin receptor(Homo sapiens (Human))
Banyu Pharmaceutical

LigandPNGBDBM29995(CHEMBL494350 | benzimidazole-based antagonist, 1)
Affinity DataIC50:  2.60nM EC50:  0.650nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Pharmaceutical

LigandPNGBDBM29995(CHEMBL494350 | benzimidazole-based antagonist, 1)
Affinity DataIC50:  0.650nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Pharmaceutical

LigandPNGBDBM29995(CHEMBL494350 | benzimidazole-based antagonist, 1)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed