BDBM29995 CHEMBL494350::benzimidazole-based antagonist, 1
SMILES C[C@@H]1CN(CCO)CCN1c1cc2[nH]c(SC(C)(C)C)nc2cc1Cl
InChI Key InChIKey=PRUISXHHETXRED-GFCCVEGCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 29995
Affinity DataIC50: 2.60nM EC50: 0.650nMpH: 7.4 T: 2°CAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
Affinity DataIC50: 0.650nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptorMore data for this Ligand-Target Pair